Billions of microorganisms, including bacteria, fungi, and archaea, are present in the human nose, which collectively form the nasal microbiome. Several studies have indicated that the nasal microbiome is an important factor for personal and global health. In fact, considerable evidence has been reported regarding the links between the gut microbiome and Parkinson’s disease (PD). Some studies have also indicated that signals from nasal microbiota reach the brain through the olfactory system and affect the nervous system function.