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Ampicillin and sulbactam
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Ampicillin and sulbactam

Generic name: ampicillin and sulbactam [ am-pi-SIL-in-and-sul-BAK-tam ]
Brand names: Unasyn, Unasyn ADD-Vantage
Dosage form: injectable powder for injection (1 g-0.5 g; 10 g-5 g; 2 g-1 g)
Drug class:Beta-lactamase inhibitors

Medically reviewed by Drugs.com on Nov 6, 2020. Written by Cerner Multum.

What is ampicillin and sulbactam?

Ampicillin and sulbactam are penicillin antibiotics that fight bacteria.

Ampicillin and sulbactam is a combination medicine used to treat many different types of infections caused by bacteria.

Ampicillin and sulbactam may also be used for purposes not listed in this medication guide.

Warnings

You should not use ampicillin and sulbactam if you have ever had a severe allergic reaction to any type of penicillin or cephalosporin antibiotic, or if you have had liver problems while using ampicillin and sulbactam.

Before taking this medicine

You should not use this medicine if you are allergic to ampicillin or sulbactam, or if you have ever had

  • a severe allergic reaction to any type of penicillin or cephalosporin antibiotic; or

  • liver problems (hepatitis or jaundice) while using ampicillin and sulbactam.

Tell your doctor if you have ever had:

Tell your doctor if you are pregnant or breastfeeding.

Do not give this medicine to a child without medical advice.

How should I use ampicillin and sulbactam?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Ampicillin and sulbactam is injected into a muscle, or given as an infusion into a vein. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself.

Ampicillin and sulbactam must be mixed with a liquid (diluent) before using it. When using injections by yourself, be sure you understand how to properly mix and store the medicine.

After mixing ampicillin and sulbactam, you will need to use it within a certain number of hours. This will depend on the diluent and how you store the mixture (at cool room temperature, or in a refrigerator).

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don't understand all instruction...