Miltefosine
Generic name: miltefosine [ MIL-te-FOE-seen ]
Brand name: Impavido
Dosage form: oral capsule (50 mg)
Drug class:Anthelmintics
What is miltefosine?
Miltefosine is an anti-parasitic drug used to treat leishmaniasis, a disease caused by an infection with parasites that enter the body through the bite of an infected sand fly.
Miltefosine is used to treat leishmaniasis affecting the skin, internal organs (such as the liver, spleen or bone marrow), and mucous membranes (nose, mouth, and throat).
Miltefosine may also be used for purposes not listed in this medication guide.
Warnings
In animal studies, miltefosine has caused birth defects and death of unborn offspring. It is not known whether these effects would occur in people. You should not use miltefosine if you are pregnant.
You may need to have a negative pregnancy test before starting this treatment. Use effective birth control while you are taking miltefosine and for at least 5 months after your treatment ends.
Before taking this medicine
You should not use miltefosine if you are allergic to it, or if you have:
a rare genetic skin and nerve disorder called Sjogren-Larsson syndrome; or
if you are pregnant.
To make sure miltefosine is safe for you, tell your doctor if you have:
liver or kidney disease.
In animal studies, miltefosine caused birth defects and death of unborn offspring, and also affected fertility in male and female adults. It is not known whether these effects would occur in people using miltefosine. Ask your doctor about your risk.
FDA pregnancy category D. You should not use miltefosine if you are pregnant. You may need to have a negative pregnancy test before starting this treatment. Use effective birth control while you are taking miltefosine and for at least 5 months after your treatment ends.
Vomiting or diarrhea caused by miltefosine can make birth control pills less effective. Ask your doctor about using non hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy if you have vomiting and/or diarrhea while taking miltefosine.
If you become pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of miltefosine on the baby.
It is not known whether miltefosine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using miltefosine, and for at l...
