Class: Tetracyclines
VA Class: AM250
CAS Number: 13614-98-7
Brands: Dynacin, Minocin, Myrac
Introduction
Antibacterial; semisynthetic tetracycline antibiotic.
Uses for Minocycline (Systemic)
Respiratory Tract Infections
Treatment of respiratory tract infections caused by Mycoplasma pneumoniae.
Treatment of respiratory tract infections caused by Haemophilus influenzae, Streptococcus pneumoniae, or Klebsiella. Should only be used for treatment of infections caused by these bacteria when in vitro susceptibility tests indicate the organism is susceptible.
Acinetobacter Infections
Alternative to imipenem or meropenem for treatment of infections caused by Acinetobacter.
Acne
Adjunctive treatment of moderate to severe inflammatory acne. Not indicated for treatment of noninflammatory acne.
Actinomycosis
Treatment of actinomycosis caused by Actinomyces israelii; oral tetracyclines (usually doxycycline or tetracycline) used as follow-up after initial parenteral penicillin G.
Amebiasis
Adjunct to amebicides for treatment of acute intestinal amebiasis. Tetracyclines not included in current recommendations for treatment of amebiasis caused by Entamoeba.
Anthrax
Alternative to doxycycline for postexposure prophylaxis to reduce the incidence or progression of disease following a suspected or confirmed exposure to aerosolized Bacillus anthracis spores (inhalational anthrax). Initial drug of choice for such prophylaxis is ciprofloxacin or doxycycline; doxycycline is the preferred tetracycline because of ease of administration and proven efficacy in monkey studies.
Alternative to doxycycline for treatment of inhalational anthrax when a parenteral regimen is not available (e.g., supply or logistic problems because large numbers of individuals require treatment in a mass casualty setting). A multiple-drug parenteral regimen (ciprofloxacin or do...
