Mipomersen
Generic name: mipomersen [ MYE-poe-mer-sen ]
Brand name: Kynamro
Dosage form: subcutaneous solution (200 mg/mL)
Drug class:Miscellaneous antihyperlipidemic agents
What is mipomersen?
Mipomersen is a cholesterol-lowering medication. It reduces blood levels of "bad" cholesterol, such as low-density lipoprotein (LDL), apolipoprotein-B (apo-B), or non-high-density lipoprotein (non-HDL).
Mipomersen is used together with a low-fat diet and other treatments to lower total cholesterol in people with homozygous familial hypercholesterolemia (an inherited type of high cholesterol). Mipomersen is not for use in people with heterozygous familial hypercholesterolemia.
It is not known whether mipomersen will lower your risk of heart disease.
Mipomersen is available only from a certified pharmacy under a special program called Kynamro REMS. Your doctor must be registered in the program in order to prescribe mipomersen for you.
Mipomersen may also be used for purposes not listed in this medication guide.
Warnings
Mipomersen is available only from a certified pharmacy.
You should not use mipomersen if you have active liver disease or abnormal liver function tests. Tell your doctor right away if you have liver symptoms, such as vomiting, fever, stomach pain, itching, tiredness, dark urine, or jaundice (yellowing of the skin or eyes).
Mipomersen can cause your liver enzymes to get too high. Your blood will need to be tested often. Your treatments may be stopped based on the results of these tests.
Before taking this medicine
You should not use mipomersen if you are allergic to it, or if you have:
active liver disease; or
abnormal liver function tests.
To make sure mipomersen is safe for you, tell your doctor if you have:
cirrhosis or other liver disease;
kidney disease (or if you are on dialysis); or
if you drink alcohol.
Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using mipomersen.
Using mipomersen during pregnancy could harm the unborn baby. Tell your doctor if you are pregnant or if you become pregnant while using mipomersen. Use effective b...
