Mitomycin
Generic name: mitomycin [ MYE-toe-MYE-sin ]
Brand name: Mutamycin
Dosage form: intravenous powder for injection (20 mg; 40 mg; 5 mg)
Drug class:Antibiotics / antineoplastics
What is mitomycin?
Mitomycin is used in combination with other cancer drugs to treat cancer of the stomach and pancreas.
Mitomycin may also be used for purposes not listed in this medication guide.
Warnings
Mitomycin can damage red blood cells, which may cause irreversible kidney failure. Tell your doctor right away if you have unusual bruising or bleeding, pale skin, confusion, tiredness or irritability, stomach pain, bloody diarrhea, red or pink urine, swelling, rapid weight gain, and little or no urinating.
Mitomycin can also weaken (suppress) your immune system, and you may get an infection more easily. Call your doctor if you have signs of infection (fever, weakness, cold or flu symptoms, skin sores, frequent or recurring illness).
Before taking this medicine
You should not be treated with mitomycin if you are allergic to it, or if you have:
low levels of platelets in your blood;
bone marrow suppression; or
active bleeding or any risk of bleeding.
Tell your doctor if you have ever had:
kidney disease;
heart disease; or
asthma, chronic obstructive pulmonary disease (COPD), sleep apnea, or other breathing disorder.
Mitomycin may harm an unborn baby. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.
You should not breastfeed while using mitomycin.
How is mitomycin given?
Mitomycin is given as an infusion into a vein. A healthcare provider will give you mitomycin.
Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when mitomycin is injected.
Some people receiving mitomycin have developed ulcers on the skin where an injection was given, or on other areas of body. Skin changes may occur several weeks or months after a mitomycin injection. Call your doctor if you notice any redness, sores, oozing, or other skin changes during or after your treatment with mitomycin.
Mitomycin affects your immune system. You may get infections more easily. You will need frequent medical tests, and your next dose may be delayed based on the results.
Mitomycin can have long las...
