Mitomycin (gel)
Generic name: mitomycin (gel) [ MYE-toe-MYE-sin ]
Brand name: Jelmyto
Dosage form: ureteral kit (40 mg)
Drug class:Antibiotics / antineoplastics
What is mitomycin gel?
Mitomycin gel is used in adults to treat cancer of the lining of the upper urinary tract including the kidney.
Mitomycin gel may also be used for purposes not listed in this medication guide.
Warnings
Mitomycin gel may cause swelling and narrowing of your ureter (the tube that urine travels through from your kidney to your bladder). Call your doctor right away if you have a fever and pain in your side or lower back.
Before taking this medicine
You should not be treated with mitomycin if you are allergic to mitomycin gel, or if you have:
a perforation (a hole or tear) in your bladder or upper urinary tract.
You may need to have a negative pregnancy test before starting this treatment.
Mitomycin gel can harm an unborn baby if the mother or the father is using this medicine.
If you are a woman, do not use mitomycin gel if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 6 months after your last dose.
If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose.
Tell your doctor right away if a pregnancy occurs while either the mother or the father is using mitomycin gel.
Do not breastfeed while using this medicine, and for at least 1 week after your last dose.
How is mitomycin gel given?
Mitomycin gel is injected directly into the kidney using a catheter inserted into the urethra (the tube for passing urine out of your bladder). A healthcare provider will give you this medicine.
Before each treatment with mitomycin gel, you will need to take another medicine called sodium bicarbonate. Carefully follow your doctor's instructions about taking this medicine.
Mitomycin gel is usually given once per week for 6 weeks.
It is very important to receive all treatments as prescribed by your doctor.
In some cases, mitomycin gel may be given for an additional 11 months after the first 6 treatments.
While receiving this medicine, your urine may appear to be violet or blue in color.
After you are treated with this medicine, your urine will contain harmful materials. For at least 6 hours after each treatment with mitomycin gel:
Use a toilet rather than a urinal and sit on the toilet while urinating. Flush the toilet several times after use.
