Mitotane
Generic name: mitotane [ MYE-toe-tane ]
Brand name: Lysodren
Dosage form: oral tablet (500 mg)
Drug class:Miscellaneous antineoplastics
What is mitotane?
Mitotane is used to treat cancer of the adrenal gland (adrenal cortical carcinoma).
Mitotane may also be used for purposes not listed in this medication guide.
Warnings
You may need to take steroid medicine, or stop taking mitotane for a short time if you have a serious injury or medical emergency. Your doctor will determine when you can start taking mitotane again. Do not change your doses or medication schedule without advice from your doctor.
You must remain under the care of a doctor while taking mitotane.
Before taking this medicine
Tell your doctor if you have ever had:
recent infection, surgery, or trauma;
liver disease; or
Do not use mitotane if you are pregnant. This medicine could harm the unborn baby or cause miscarriage or premature birth. Use effective birth control to prevent pregnancy while you are using mitotane.
Do not breastfeed while using this medicine.
Follow your doctor's instructions about how long to avoid pregnancy and breastfeeding after your treatment ends. Mitotane can stay in your bloodstream long after you stop using it.
How should I take mitotane?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
You may need frequent medical tests. Even if you have no symptoms, tests can help your doctor determine if mitotane is effective.
You may need to take steroid medicine, or stop taking mitotane for a short time if you have a serious injury or medical emergency. Your doctor will determine when you can start taking this medicine again. Do not change your doses or medication schedule without advice from your doctor.
You must remain under the care of a doctor while taking mitotane.
Store mitotane at room temperature away from moisture and heat.
Ask your pharmacist how to safely handle mitotane tablets. You may need to wear latex gloves when handling this medicine. Do not use a broken tablet.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.