Moexipril and hydrochlorothiazide (Oral)
Medically reviewed by Drugs.com. Last updated on Apr 19, 2022.
Discontinue moexipril hydrochloride and hydrochlorothiazide as soon as possible once pregnancy is detected since drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus .
Commonly used brand name(s)
In the U.S.
- Uniretic
Pharmacologic Class: Diuretic
Chemical Class: Thiazide
Uses for moexipril and hydrochlorothiazide
Moexipril and hydrochlorothiazide combination is used to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure reduces the risk of strokes and heart attacks.
Moexipril is an angiotensin converting enzyme (ACE) inhibitor. It works by blocking a substance in the body that causes blood vessels to tighten. As a result, moexipril relaxes the blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart.
Hydrochlorothiazide is a thiazide diuretic (water pill). It reduces the amount of water in the body by increasing the flow of urine, which helps lower blood pressure.
Moexipril and hydrochlorothiazide is available only with your doctor's prescription.
Before using moexipril and hydrochlorothiazide
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For moexipril and hydrochlorothiazide, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to moexipril and hydrochlorothiazide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of moexipril and hydrochlorothiazide combination in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of moexipril and hydrochlorothiazide combination in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and a dose adjustment for patients receiving moexipril and hydrochlorothiazide combination.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking moexipril and hydrochlorothiazide, it is..
