Anakinra
Generic name: anakinra [ an-na-KIN-rah ]
Brand name: Kineret
Dosage form: subcutaneous solution (100 mg/0.67 mL)
Drug classes:Antirheumatics, Interleukin inhibitors
What is anakinra?
Anakinra is used to treat the symptoms of moderate to severe rheumatoid arthritis in adults. Anakinra may also help slow the progress of the disease. Anakinra is usually given after other arthritis medications did not work or have stopped working.
Anakinra is also used in newborn babies to treat a rare genetic condition called neonatal onset multisystem inflammatory disease (NOMID). NOMID is a form of cryopyrin-associated periodic syndromes (CAPS). This condition causes uncontrolled inflammation in many parts of the body, including the skin, joints, and central nervous system.
Anakinra is also used to control symptoms of a condition called Deficiency of Interleukin-1 Receptor Antagonist (DIRA) in adults and children. DIRA is a very rare genetic condition that causes a severe inflammatory reaction during the first days of life and can lead to organ failure throughout the body.
Anakinra may also be used for purposes not listed in this medication guide.
Warnings
You should not use anakinra if you are allergic to medicines that contain E. coli bacteria proteins, or if you have an active infection.
Before taking this medicine
You should not use this medicine if you are allergic to anakinra or if you have:
an active infection; or
an allergy to any medicine that contains E. coli bacteria proteins.
Tell your doctor if you have ever had:
kidney disease;
an active or chronic infection;
fever, chills, or open sores on your skin;
a weak immune system (caused by disease or by using certain medicines):
asthma; or
Tell your doctor if you are pregnant or plan to become pregnant. Having rheumatoid arthritis or CAPS during pregnancy may increase the risk of premature birth or low birth weight. The benefit of treating rheumatoid arthritis or CAPS may outweigh any risks to the baby.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
Do not give this medicine to a child without medical advice. Anakinra is not approved to treat rheumatoid arthritis in anyone younger than 18 years old.
How should I use anakinra?
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