Mylotarg

Generic name:gemtuzumab ozogamicin [ jem-TOOZ-ue-mab-OH-zoe-ga-MYE-sin ]
Drug class:CD33 monoclonal antibodies

Medically reviewed by Philip Thornton, DipPharm. Last updated on Mar 29, 2021.

What is Mylotarg?

Mylotarg is a monoclonal antibody linked to a chemotherapy drug. Monoclonal antibodies are made to target and destroy only certain cells in the body. This may help to protect healthy cells from damage.

Mylotarg is used to treat a certain type (CD33-positive) of newly-diagnosed acute myeloid leukemia in adults and children at least 1 month old.

Mylotarg is also used to treat CD33-positive acute myeloid leukemia after other treatments did not work or have stopped working in adults and children at least 2 years old.

Warnings

Mylotarg can increase your risk of bleeding or liver damage, either of which may be life-threatening.

Call your doctor at once if you have upper stomach pain, yellowing of your skin or eyes, rapid weight gain, swelling in your midsection, sudden numbness or weakness, problems with speech or vision, severe headache, or unusual bleeding (bleeding gums, vaginal bleeding, blood in your urine or stools, coughing up blood).

Before taking this medicine

You should not be treated with Mylotarg if you are allergic to gemtuzumab ozogamicin.

To make sure Mylotarg is safe for you, tell your doctor if you have:

• liver disease;

• long QT syndrome (in you or a family member);

• a stem cell transplant; or

• an electrolyte imbalance (such as low levels of potassium or magnesium in your blood).

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