Anatrast Paste

Generic name:barium sulfate
Dosage form: paste
Drug class:Non-iodinated contrast media

Medically reviewed by Drugs.com. Last updated on Jul 22, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

Anatrast Paste Description

Anatrast is a cherry flavored, ready-to-use barium sulfate USP suspension paste. It is a contrast medium developed for defecography.

The product contains 100% w/v (56% w/w) barium sulfate USP, sorbitol, suspending and dispersing agents, simethicone, flavoring, preservatives and water. Barium sulfate has the empirical formula BaSO4.

Anatrast Paste - Clinical Pharmacology

Barium sulfate is an insoluble material which, because of its density, provides a positive contrast during x-ray examination. Barium sulfate is an inert radiopaque material which is not absorbed or metabolized and is eliminated intact from the body in a manner similar to other non-absorbed inorganic materials.

Indications and Usage for Anatrast Paste

Anatrast is indicated for use in defecography.

Contraindications

Barium sulfate products are contraindicated in patients with known or suspected obstruction of the colon, known or suspected gastrointestinal tract perforation, inflammation or neoplastic lesions of the rectum, recent rectal biopsy, or known hypersensitivity to barium sulfate formulations.

Known hypersensitivity or allergy to latex is a contraindication for the use of balloon retention enema tips containing latex.

The use of a retention cuff enema tip is not necessary or desirable in patients with normal sphincter tone. The presence of adequate sphincter tone can be judged by preliminary rectal digital examination.

Warnings

Serious adverse reactions, including death, have been reported with the administration of barium sulfate formulations and are usually associated with the technique of administration, the underlying pathological condition and/or patient hypersensitivities.

In patients with increased intracranial pressure, barium sulfate suspension enemas present an additional risk of further increasing intracranial pressure.

Care must be taken during the insertion of an enema tip into the p...