Andexxa

Generic name:coagulation factor Xa [ koe-AG-ue-LAY-tion-FAK-tor-Xa ]
Drug class:Anticoagulant reversal agents

Medically reviewed by Drugs.com on Apr 7, 2022. Written by Cerner Multum.

What is Andexxa?

Andexxa is a protein that reverses the effects of certain anticoagulant medications that are used to treat or prevent blood clots. Reversing anticoagulant medicine is necessary if you have uncontrolled or life-threatening bleeding as a result of how that medicine works.

Andexxa is used to treat uncontrolled bleeding in people who take the anticoagulantsrivaroxaban (Xarelto) and apixaban (Eliquis).

Andexxa was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, healthy volunteers responded to Andexxa, but further studies are needed.

Andexxa may also be used for purposes not listed in this medication guide.

Warnings

This medicine is used to reverse the effects of anticoagulant medication, which may increase your risk of a blood clot, heart attack, stroke, or death. Watch for symptoms such as chest pain, sudden numbness or weakness, problems with vision or speech, and swelling or redness in an arm or leg.

Before taking this medicine

You should not be treated with Andexxa if you have had an allergic reaction to clotting factor medicine.

In an emergency, you may not be able ...