Natazia

Generic name:dienogest and estradiol [ dye-EN-oh-jest-and-ESS-tra-DYE-ole ]
Drug class:Contraceptives

Medically reviewed by Drugs.com. Last updated on Jan 25, 2022.

What is Natazia?

Natazia contains a combination of dienogest and estradiol. Dienogest and estradiol are female hormones that prevent ovulation (the release of an egg from an ovary). This medicine also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.

Natazia is used to prevent pregnancy.

Natazia is also used to treat heavy menstrual bleeding that is not caused by any medical condition of the uterus.

Warnings

Do not use Natazia if you are pregnant or if you have recently had a baby.

You should not take Natazia if you have any of the following conditions: uncontrolled high blood pressure, heart disease, a blood-clotting disorder, circulation problems, diabetic problems with your eyes or kidneys, unusual vaginal bleeding, liver disease or liver cancer, severe migraine headaches, if you smoke and are over 35, or if you have ever had breast or uterine cancer, a heart attack, a stroke, or a blood clot.

Taking Natazia can increase your risk of blood clots, stroke, or heart attack, especially if you have certain other conditions, or if you are overweight.

Smoking can greatly increase your risk of blood clots, stroke, or heart attack. You should not take Natazia if you smoke and are over 35 years old.

Missing a pill increases your risk of becoming pregnant. Carefully follow the "missed dose" instructions if you forget to take your medicine.

Some drugs can make Natazia less effective in preventing pregnancy, including antibiotics, hepatitis C medications, HIV/AIDS medications, seizure medications, or barbiturate sedatives. Tell your doctor about all other medications you use.

Before taking this medicine

Taking Natazia can increase your risk of blood clots, stroke, or heart attack. You are even more at risk if you have high blood pressure, diabetes, high cholesterol, or if you are overweight. Your risk of stroke or blood clot is highest during your first year of taking Natazia. Your risk is also high when you restart this medicine after not taking it for 4 weeks or longer.

Smoking can greatly increase your risk of blood clots, stroke, or heart attack. Your risk increases the older you are and the more you smoke. You should not take Natazia if you smoke and are over 35 years old.

Do not use if you are pregnant. Stop taking Natazia and tell your doctor if you become pregnant, or if you miss two menstrual periods in a row. If you have recently had a baby, wait at least 4 weeks before taking this medicine.

You should not take Natazia if you have:

• untreated or uncontrolled high blood pressure;

• heart disease (coronary artery disease, uncontrolled heart valve disorder, history of heart attack, stroke, or blood clot);

• a blo...