Navelbine

Generic name:vinorelbine [ vin-OR-el-been ]
Drug class:Mitotic inhibitors

Medically reviewed by Drugs.com on Apr 12, 2021. Written by Cerner Multum.

What is Navelbine?

Navelbine is used to treat non-small cell lung cancer, sometimes used in combination with other cancer medications.

Navelbine may also be used for other purposes not listed in this medication guide.

Warnings

You may get infections more easily, even serious or fatal infections. Call your doctor if you have a fever, chills, tiredness, cough, skin sores, bruising, pale skin, unusual bleeding, or trouble breathing.

Before taking this medicine

You should not be treated with Navelbine if you are allergic to it, or if you have severely low white blood cell counts.

Tell your doctor if you have ever had:

liver disease;
bone marrow suppression;
a nerve disorder; or
radiation therapy or other cancer treatments.

Navelbine can harm an unborn baby or cause birth defects if the mother or the father is using Navelbine.

If you are a woman, you may need to have a negative pregnancy test before starting this treatment. Do not use Navelbine if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 6 months after your last dose.
If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose.
Tell your doctor right away if a pregnancy occurs while either the mother or the father is using Navelbine.

Navelbine can damage sperm and it may be harder for you to get a woman pregnant while you are using this medicine. You should still use birth control to prevent pregnancy because the medicine can harm an unborn baby.

You should not breastfeed while using Navelbine, and for at least 9 days after your last dose.

How is Navelbine given?

Navelbine is given as an infusion into a vein. A healthcare provider will give you this injection.

Navelbine is usually given once every 7 days to 6 weeks. Your schedule will depend on the condition being treated. Follow your doctor's dosing instructions very carefully.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Navelbine is injected.

Navelbine affects your immune system. You may get infections more easily, even serious or fatal infections. Your blood will need to be tested often and your treatment may be delayed based on the results.