Navelbine Injection
Generic name:vinorelbine tartrate
Dosage form: injection
Drug class:Mitotic inhibitors
Medically reviewed by Drugs.com. Last updated on Dec 22, 2021.
On This Page
- Boxed Warning
- Indications and Usage
- Dosage and Administration
- Dosage Forms and Strengths
- Contraindications
- Warnings and Precautions
- Adverse Reactions/Side Effects
- Drug Interactions
- Use In Specific Populations
- Overdosage
- Description
- Clinical Pharmacology
- Nonclinical Toxicology
- Clinical Studies
- References
- How Supplied/Storage and Handling
- Patient Counseling Information
WARNING: MYELOSUPPRESSION
- Severe myelosuppression resulting in serious infection, septic shock, hospitalization and death can occur [see Warnings and Precautions (5.1)].
- Decrease the dose or withhold NAVELBINE in accord with recommended dose modifications [see Dosage and Administration (2.2)].
Indications and Usage for Navelbine Injection
NAVELBINE is a vinca alkaloid indicated:
- In combination with cisplatin for first-line treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC)
- As a single agent, for the treatment of patients with metastatic NSCLC
DOSAGE AND ADMINISTRATION
Recommended Dosage
In Combination with Cisplatin 100 mg/m2
- The recommended dose of NAVELBINE is 25 mg/m 2 administered as an intravenous injection or infusion over 6 to 10 minutes on Days 1, 8, 15, and 21 of a 28 day cycle in combination with cisplatin 100 mg/m 2 on Day 1 only of each 28 day cycle.
In Combination with Cisplatin 120 mg/m2
- The recommended dose of NAVELBINE is 30 mg/m 2 administered as an intravenous injection or infu...
