Neomycin, Polymyxin B, Dexamethasone

Generic name: neomycin sulfate, polymyxin B sulfate, dexamethasone
Dosage form: ophthalmic suspension
Drug class:Ophthalmic steroids with anti-infectives

Medically reviewed by Drugs.com. Last updated on Sep 1, 2020.

Neomycin, Polymyxin B, Dexamethasone Description

Neomycin and Polymyxin B Sulfates and Dexamethasone Ophthalmic Suspension, USP is a multiple dose anti-infective steroid combination in sterile suspension form for topical application. The chemical structure for the active ingredient, dexamethasone, is:

C22H29FO5

392.46

Established name: dexamethasone

Chemical name: pregna-1, 4-diene-3, 20-dione, 9-fluoro-11,17, 21-trihydroxy-16-methyl-, (11β,16α)-.

The other active ingredients are neomycin sulfate and polymyxin B sulfate. The structural formula for neomycin sulfate is:

: C23H46N6O13’χH2SO4Mᵣ 615 (base)

The structural formula for polymyxin B sulfate is:

: C56H98N16O13 1203.48

Each mL contains: Actives: neomycin sulfate equivalent to neomycin 3.5 mg, polymyxin B sulfate 10,000 units, dexamethasone 0.1%. Inactives: hypromellose 2910 0.5%, sodium chloride, polysorbate 20, hydrochloric acid and/or sodium hydroxide (to adjust pH), purified water, benzalkonium chloride 0.004% (preservative).