NeoProfen

Generic name:ibuprofen injection [ EYE-bue-proe-fen ]
Brand names: Caldolor, NeoProfen
Drug class:Nonsteroidal anti-inflammatory drugs

Medically reviewed by Drugs.com on May 5, 2022. Written by Cerner Multum.

What is ibuprofen?

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to reduce fever and treat pain.

Neoprofen is used in premature babies to treat a condition called patent ductus arteriosus (an abnormal blood vessel opening that normally closes shortly after birth).

Ibuprofen may also be used for purposes not listed in this medication guide.

Warnings

Ibuprofen can increase your risk of fatal heart attack or stroke. Do not use NeoProfen just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Ibuprofen may also cause stomach or intestinal bleeding, which can be fatal.

Before taking this medicine

Ibuprofen can increase your risk of fatal heart attack or stroke. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Ibuprofen may also cause stomach or intestinal bleeding, which can be fatal. This can occur without warning, especially in older adults.

You should not be treated with ibuprofen if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.

Tell your doctor if you have ever had:

• heart disease, high blood pressure, high cholesterol, diabetes, or if you smoke;

• a heart attack, stroke, or blood clot;

• stomach ulcers or bleeding;

• asthma;

• liver or kidney disease;

• fluid retention; or

• a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, or lupus.

If you are pregnant, you should not take ibuprofen unless your doctor tells you to. Taking an NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy.

Ask a doctor if it is safe to breastfeed while using this medicine.

How is NeoProfen given?

Ibuprofen is injected into a vein by a healthcare provider.

Drink plenty of liquids while you are receiving NeoProfen.