#
Nexletol
  • Treatments
  • High Cholesterol
  • Familial Heterozygous

Nexletol

Generic name:bempedoic acid
Drug class:Miscellaneous antihyperlipidemic agents

Medically reviewed by Judith Stewart, BPharm. Last updated on Feb 21, 2022.

What is Nexletol?

Nexletol is a prescription medicine used along with diet and other lipid-lowering medicines in the treatment of adults with:

  • heterozygous familial hypercholesterolemia (HeFH). HeFH is an inherited condition that causes high levels of “bad” cholesterol called low density lipoprotein (LDL).
  • known heart disease who need additional lowering of “bad” cholesterol (LDL-C) levels.

It is not known if Nexletol can decrease problems from high cholesterol, such as heart attacks, stroke, death, or other heart problems.It is not known if Nexletol is safe and effective in people with severe kidney problems including people with end-stage kidney disease who are on dialysis.
It is not known if Nexletol is safe and effective in people with severe liver problems.
It is not known if Nexletol is safe and effective in children under 18 years of age.

Before taking Nexletol

Before you start taking Nexletol, tell your healthcare provider about all your medical conditions, including if you:

  • have or had gout.
  • have or had tendon problems.
  • are pregnant. Tell your healthcare provider right away if you become pregnant while taking Nexletol. You and your healthcare provider will decide if you should take Nexletol while you are pregnant.
  • are breastfeeding or plan to breastfeed. It is not known if Nexletol passes into your breast milk. You and your healthcare provider should decide if you will take Nexletol or breastfeed. You should not do both.
  • have severe kidney problems.
  • have severe liver problems.

Nexletol may affect the way other medicines work, and other medicines may affect how Nexletol works. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal suppl.