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Nifurtimox
  • Treatments
  • Trypanosomiasis

Nifurtimox

Generic name: nifurtimox [ nye-FURE-ti-mox ]
Brand name: Lampit
Dosage form: oral tablet (120 mg; 30 mg)
Drug class:Miscellaneous antibiotics

Medically reviewed by Drugs.com on Dec 1, 2020. Written by Cerner Multum.

What is nifurtimox?

Nifurtimox is used to treat Chagas disease, a condition caused by a parasite. Chagas disease occurs most commonly in Mexico, Central America, and South America.

Nifurtimox is for use in children from birth through their 17th year. A child must weigh at least 5.5 pounds (2.5 kilograms) before taking nifurtimox.

Nifurtimox may also be used for purposes not listed in this medication guide.

Warnings

Follow all directions on your medicine label and package. Tell each of your child's healthcare providers about all the child's medical conditions, allergies, and all medicines the child uses.

Before taking this medicine

Your child should not use nifurtimox if he or she is allergic to it.

Tell your child's doctor if the child has ever had:

  • a brain injury;

  • a seizure;

  • mental illness or psychosis;

  • kidney disease (or if the child is on dialysis);

  • liver disease; or

  • porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system).

Nifurtimox can harm an unborn baby if the mother or the father is using nifurtimox. Sexually active females and males should use effective birth control.

  • If you are female, you may need to have a negative pregnancy test before starting this treatment. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 6 months after your last dose.

  • If you are male, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose.

  • Tell your doctor right away if a pregnancy occurs while either the mother or the father is using nifurtimox.

If you are breastfeeding, tell your doctor if you notice symptoms in the nursing baby such as fussiness, decreased appetite, vomiting, rash, or fever.

How should I use nifurtimox?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your child's dose. Use the medicine exactly as directed.

The usual dosage of nifurtimox is 3 times per day with food, taken for 60 days. Follow your doctor's dosing instructions very carefully.

Each tablet should be swallowed who...