Class: Nitrates and Nitrites
VA Class: CV250
Chemical Name: Trinitrate 1,2,3-propanetriol
Molecular Formula: C3H5N3O9
CAS Number: 55-63-0
Brands: GoNitro, Minitran, Nitro-Bid, Nitro-Dur, Nitrolingual, NitroMist, Nitrostat, Nitro-Time
Warning
Special Alerts:
A standardized concentration for this drug has been established through Standardize 4 Safety (S4S), a national patient safety initiative to reduce medication errors, especially during transitions of care. The drug is included in a standard concentration list which may apply to an IV or oral compounded liquid formulation. For additional information, see the ASHP website [Web].
Introduction
Nitroglycerin, an organic nitrate, is a vasodilating agent.
Uses for Nitroglycerin (Systemic)
Chronic Stable Angina
Management of angina pectoris secondary to CAD.
Short-acting preparations (e.g., sublingual nitroglycerin tablets, nitroglycerin spray) used for acute relief of angina; also may be used for acute prophylactic management in situations likely to provoke angina attacks.
Sublingual nitroglycerin is considered the drug of choice for acute relief of angina pectoris because it has a rapid onset of action, is inexpensive, and its efficacy is well established.
Long-acting preparations (e.g., oral or topical nitroglycerin) used for long-term prophylactic management of chronic stable angina.
While β-blockers are recommended as the anti-ischemic drugs of choice in most patients with chronic stable angina, long-acting nitroglycerin preparations may be substituted or added in patients who do not tolerate or respond adequately to β-blockers.
Non-ST-Segment-Elevation Acute Coronary Syndromes (NSTE ACS)
Acute symptomatic relief of chest pain...
