Generic name:desmopressin (nasal route) [ des-moe-PRES-in ]
Drug class:Antidiuretic hormones
Medically reviewed by Drugs.com. Last updated on Jan 2, 2022.
Noctiva(TM) can cause hyponatremia. Severe hyponatremia can be life-threatening, leading to seizures, coma, respiratory arrest or death. Noctiva(TM) is contraindicated in patients at increased risk of severe hyponatremia, such as patients with excessive fluid intake, illnesses that can cause fluid or electrolyte imbalances (eg, gastroenteritis, salt-wasting nephropathies, or systemic infection), and in those using loop diuretics or systemic or inhaled glucocorticoids. Ensure serum sodium concentrations are normal before starting or resuming Noctiva(TM). Measure serum sodium within 7 days and approximately 1 month after initiating therapy or increasing the dose, and periodically during treatment. More frequently monitor serum sodium in patients 65 years of age and older and in patients at increased risk of hyponatremia. If hyponatremia occurs, Noctiva(TM) may need to be temporarily or permanently discontinued .
Commonly used brand name(s)
In the U.S.
- DDAVP
- DDAVP Rhinal Tube
- Minirin
- Noctiva
- Stimate
Available Dosage Forms:
- Solution
- Spray
Therapeutic Class: Endocrine-Metabolic Agent
Pharmacologic Class: Vasopressin (class)
Uses for Noctiva
Desmopressin nasal spray is used to treat central cranial diabetes insipidus. This is a condition that causes the body to lose too much fluid and become dehydrated. It is also used to control frequent urination and increased thirst caused by certain types of brain injury or brain surgery. The Stimate® nasal spray is used to treat bleeding in patients with hemophilia A or von Willebrand disease (Type I).
Noctiva™ nasal spray is used to treat nocturnal polyuria in adults who awaken two or more times to urinate at night. Nocturnal polyuria is a condition where your body makes too much urine at night. Your doctor will need to measure your urine..
