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Nuedexta
  • Treatments
  • Pseudobulbar Affect

Nuedexta

Generic name:dextromethorphan and quinidineDEX-troe-me-THOR-fan-and-KWIN-i-deen ]
Drug class:Miscellaneous central nervous system agents

Medically reviewed by Philip Thornton, DipPharm. Last updated on Sep 28, 2021.

What is Nuedexta?

Nuedexta contains a combination of dextromethorphan and quinidine. Dextromethorphan affects the signals in the brain that trigger cough reflex and is generally used as a cough suppressant. Quinidine affects the way that the heart beats and is generally used in people with certain heart rhythm disorders.

Nuedexta is used for the treatment of pseudobulbar affect (PBA).

Nuedexta treats involuntary outbursts of crying or laughing in people with certain neurological disorders, including multiple sclerosis and amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease).

Warnings

You should not use Nuedexta if you have heart failure, a serious heart condition called "AV block" (unless you have a pacemaker), or a history of Long QT syndrome or life-threatening heart rhythm disorder.

Do not use Nuedexta if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

You also should not take Nuedexta if you are also taking mefloquine, quinidine, or quinine, or if you have ever had an allergic reaction or serious medical problem caused by taking any of these medications.

Some medicines can interact with Nuedexta and should not be used at the same time. Tell your...