NuLev MeltTablets
Generic name:hyoscyamine sulfate
Dosage form: tablet, chewable
Drug class:Anticholinergics / antispasmodics
Medically reviewed by Drugs.com. Last updated on Apr 21, 2022.
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The NuLev brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
NuLev MeltTablets Description
Each round, white, peppermint flavored tablet can be chewed or placed on tongue for disintegration and contains 0.125 mg of hyoscyamine sulfate USP.
Hyoscyamine sulfate is one of the principal anticholinergic/antispasmodic components of belladonna alkaloids. The empirical formula is (C17H23NO3)2•H2SO4•2H2O and the molecular weight is 712.85. Chemically, it is benzeneacetic acid, α-(hydroxymethyl)-, 8-methyl-8-azabicyclo [3.2.1.] oct-3-yl ester, [3(S)-endo]•, sulfate (2:1), dehydrate with the following structure:
Inactive ingredients include: lactose monohydrate, magnesium stearate, mannitol USP, peppermint flavor, starch, stearic acid.
NuLev MeltTablets - Clinical Pharmacology
Hyoscyamine sulfate inhibits specifically the actions of acetylcholine on structures innervated by postganglionic cholinergic nerves and on smooth muscles that respond to acetylcholine but lack cholinergic innervation. These peripheral cholinergic receptors are present in the autonomic effector cells of the smooth muscle, cardiac muscle, the sinoatrial node, the atrioventricular node, and the exocrine glands. At therapeutic doses, it is complete...
