Ocudox
Generic name:doxycycline hyclate
Dosage form: capsule
Drug classes:Miscellaneous antimalarials, Tetracyclines
Medically reviewed by Drugs.com. Last updated on Nov 22, 2021.
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The Ocudox brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Description
Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline, and is available as doxycycline hyclate (doxycycline hydrochloride hemiethanolate hemihydrate) capsules and tablets for oral administration. The chemical designation of this light-yellow crystalline powder is alpha-6-deoxy-5-oxytetracycline. Doxycycline has a high degree of lipoid solubility and a low affinity for calcium binding. It is highly stable in normal human serum. Doxycycline will not degrade into an epianhydro form. Doxycycline hyclate has the following structural formula:
(C22H24N2O8•HCl)2•C2H6O•H2O M.W. 1025.89
Each capsule for oral administration contains 50 mg or 100 mg doxycycline hyclate, equivalent to 50 mg or 100 mg doxycycline (anhydrous). Inactive ingredients for capsules are: anhydrous lactose, croscarmellose sodium, D and C Red #28, FD and C Blue #1, gelatin, magnesium stearate, microcrystalline cellulose, titanium dioxide. Each tablet for oral administration contains 100 mg doxycycline hyclate, equivalent to 100 mg doxycycline. Inactive ingredients for tablets are: anhydrous lactose, carnauba wax, croscarmellose sodium, D and C Yellow #10 aluminum lake, FD and C Red #40 aluminum lake, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, titanium dioxide.
Clinical Pharmacology
Tetracyclines are readily absorbed and are bound to plasma proteins in varying degree. They are concentrated by the...
