Class: Quinolones
VA Class: AM900
Chemical Name: ±-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxaz ine-6-carboxylicacid
CAS Number: 82419-36-1
Warning
- Serious Adverse Reactions
Fluoroquinolones, including ofloxacin, have been associated with disabling and potentially irreversible serious adverse reactions (e.g., tendinitis and tendon rupture, peripheral neuropathy, CNS effects) that have occurred together. Discontinue immediately and avoid use of fluoroquinolones, including ofloxacin, in patients who have experienced any of these serious adverse reactions. (See Warnings under Cautions.)
Fluoroquinolones, including ofloxacin, may exacerbate muscle weakness in patients with myasthenia gravis. Avoid in patients with known history of myasthenia gravis.
Because of risk of serious adverse reactions, use ofloxacin for treatment of acute bacterial exacerbations of chronic bronchitis or uncomplicated urinary tract infections (UTIs) only when no other treatment options available.
Introduction
Antibacterial; fluoroquinolone.
Uses for Ofloxacin (Systemic)
Respiratory Tract Infections
Treatment of acute bacterial exacerbations of chronic bronchitis caused by susceptible Haemophilus influenzae or Streptococcus pneumoniae.
Use for treatment of acute bacterial exacerbations of chronic bronchitis only when no other treatment options available.Because systemic fluoroquinolones, including ofloxacin, have been associated with disabling and potentially irreversible serious adverse reactions (e.g., tendinitis and tendon rupture, peripheral neuropathy, CNS effects) that can occur together in the same patient (see Cautions) and because acute bacterial exacerbations of chronic bronchitis may be self-limiting in some patients,risks of serious adverse reactions outw..
