Oforta
Generic name:fludarabine (oral) [ floo-DAR-a-been ]
Drug class:Antimetabolites
Medically reviewed by Drugs.com. Last updated on Jun 29, 2021.
The Oforta brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
What is Oforta?
Oforta is a cancer medication that interferes with the growth and spread of cancer cells in the body.
Oforta is used to treat B-cell chronic lymphocytic leukemia (CLL). It is usually given after other cancer medications have been tried without successful response to treatment.
Oforta may also be used for other purposes not listed in this medication guide.
Warnings
Do not use Oforta if you are pregnant. It could harm the unborn baby. Use birth control to prevent pregnancy while you are taking this medicine, whether you are a man or a woman. Keep using birth control for at least 6 months after your treatment ends. Use of fludarabine by either parent may cause birth defects.
Before you take Oforta, tell your doctor if you have kidney disease, bone marrow problems, or a weak immune system.
Oforta can lower blood cells that help your body fight infections and help your blood to clot. Serious and sometimes fatal infections may occur during treatment. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, painful mouth sores, cold or flu symptoms, pale or yellowed skin, dark colored urine).
Oforta may also have harmful effects on your lungs. Call your doctor at once if you have a new or worsening cough, fever, and trouble breathing.
Oforta can affect your central nervous system during or just after treatment. Get emergency medical help if you have vision problems, confusion, agitation, changes in behavior, or a light-headed feeling (like you might pass out).
Before I take Oforta
You should not use Oforta if you are allergic to fludarabine, or if you are also being treated with pentostatin (Nipent).
To make sure Oforta is safe for you, tell your doctor if you have:
kidney disease; or
bleeding or blood clotting disorder.
FDA pregnancy category D. Do not use Oforta if you are pregnant. It could harm the unborn baby.
Use birth control to prevent pregnancy while you are taking Oforta, and for at least 6 months after your treatment ends whether you are a man or a woman. Oforta use by either parent may cause birth defects.
It is not known whether fludarabine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are taking this medicine.
