Olopatadine and mometasone (Nasal)

Medically reviewed by Drugs.com. Last updated on Apr 19, 2022.

Commonly used brand name(s)

In the U.S.

• Ryaltris

Pharmacologic Class: Olopatadine

Uses for olopatadine and mometasone

Olopatadine and mometasone combination nasal spray is used to treat symptoms (eg, stuffy or runny nose, itching, sneezing) of seasonal (short-term) allergic rhinitis (hay fever).

Olopatadine is an antihistamine. It works by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes.

Mometasone belongs to the family of medicines known as corticosteroids (cortisone-like medicines). It works by preventing certain cells from releasing substances that cause an allergic reaction.

Olopatadine and mometasone is available only with your doctor's prescription.

Before using olopatadine and mometasone

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For olopatadine and mometasone, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to olopatadine and mometasone or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of olopatadine and mometasone combination nasal spray in children 12 years of age and older. However, safety and efficacy have not been established in children younger than 12 years of age.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of olopatadine and mometasone combination nasal spray in the elderly.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking olopatadine and mometasone, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using olopatadine and mometasone with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Desmopressin

Using olopatadine and mometasone with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Amifampridine
• Bemiparin
• Bupropion
• Cobicistat
• Donepezil
• Lutetium Lu 177 Dotatate
• Macimorelin
• Nadroparin
• Nirmatrelvir
• Pitolisant
• Ritonavir
• Sargramostim

Using olopatadine and...