Omacetaxine
Generic name: omacetaxine [ OH-ma-se-TAX-een ]
Brand name: Synribo
Dosage form: subcutaneous powder for injection (3.5 mg)
Drug class:Miscellaneous antineoplastics
What is omacetaxine?
Omacetaxine is used to treat chronic myeloid leukemia (CML).
Omacetaxine is given after at least two other cancer treatments did not work or have stopped working.
Omacetaxine may also be used for purposes not listed in this medication guide.
Warnings
Omacetaxine can increase your risk of bleeding or infection. Call your doctor if you have unusual bruising or bleeding, blood in your urine or stools, confusion, problems with vision or speech, or new signs of infection (fever, chills, tiredness, body aches, feeling short of breath).
Before taking this medicine
You should not use omacetaxine if you are allergic to it.
Tell your doctor if you have ever had:
diabetes (in you or a family member); or
bleeding problems.
Omacetaxine can harm an unborn baby or cause birth defects if the mother or the father is using omacetaxine.
If you are a woman, do not use omacetaxine if you are pregnant. You may need to have a negative pregnancy test before starting this treatment. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 6 months after your last dose.
If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose.
Tell your doctor right away if a pregnancy occurs while either the mother or the father is using omacetaxine.
This medicine may affect fertility (ability to have children) in men. However, it is important to use birth control to prevent pregnancy because omacetaxine can harm an unborn baby.
Do not breastfeed while using this medicine, and for at least 2 weeks after your last dose.
How is omacetaxine given?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Omacetaxine is injected under the skin. A healthcare provider may teach you how to properly use the medication by yourself.
Omacetaxine is usually given every 12 hours. Do not change your dosing schedule or stop using this medicine unless your doctor tells you to.
Your healthcare provider will show you where on your body to inject omacetaxine. Use a different place each time you give an injection. Do not inject into the same place two times in a row.
Your injection will be prepared at the pharmacy and you will receive the medicine in prefilled syringes...
