Ombitasvir, paritaprevir, ritonavir and dasabuvir (Oral)
Medically reviewed by Drugs.com. Last updated on Feb 19, 2022.
Test all patients for evidence of current or prior hepatitis B virus (HBV) infection before initiating treatment with ombitasvir/paritaprevir/ritonavir/dasabuvir. HBV reactivation has been reported in hepatitis C virus (HCV)/HBV coinfected patients who were undergoing or had completed treatment with HCV direct acting antivirals and were not receiving HBV antiviral therapy. Some cases have resulted in fulminant hepatitis, hepatic failure, and death. Monitor HCV/HBV coinfected patients for hepatitis flare or HBV reactivation during HCV treatment and post-treatment follow-up. Initiate appropriate patient management for HBV infection as clinically indicated .
Commonly used brand name(s)
In the U.S.
- Viekira Pak
Available Dosage Forms:
- Tablet
Uses for ombitasvir, paritaprevir, ritonavir and dasabuvir
Ombitasvir, paritaprevir, ritonavir, and dasabuvir combination is used with or without ribavirin to treat chronic hepatitis C infection, including patients with compensated cirrhosis.
Ombitasvir, paritaprevir, ritonavir and dasabuvir is available only with your doctor's prescription.
Before using ombitasvir, paritaprevir, ritonavir and dasabuvir
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For ombitasvir, paritaprevir, ritonavir and dasabuvir, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to ombitasvir, paritaprevir, ritonavir and dasabuvir or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of Viekira Pak® in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of Viekira Pak® in the elderly.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking ombitasvir, paritaprevir, ritonavir and dasabuvir, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using ombitasvir, paritaprevir, ritonavir and dasabuvir with any of the following medicines is not recommended. Your doctor may decide not to treat you with this..
