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Omeprazole
  • Treatments
  • GERD

Omeprazole

Generic name: omeprazole [ oh-MEP-ra-zol ]
Brand names: FIRST Omeprazole, Omeprazole + SyrSpend SF Alka, PriLOSEC, PriLOSEC OTC, Zegerid (Original Formulation)
Dosage forms: oral delayed release capsule (10 mg; 20 mg; 40 mg); oral delayed release tablet (20 mg); oral powder for reconstitution, delayed release (10 mg; 2.5 mg); oral suspension (2 mg/mL)
Drug class:Proton pump inhibitors

Medically reviewed by Melisa Puckey, BPharm. Last updated on May 23, 2022.

What is omeprazole?

Omeprazole is used to treat excess stomach acid in conditions such as non cancerous stomach ulcers, gastroesophageal reflux disease (GERD), active duodenal ulcer, Zollinger-Ellison syndrome and erosive esophagitis. Omeprazole works by blocking gastric acid production and is from the group of medicines called proton pump inhibitors.

Omeprazole may also be given together with antibiotics to treat gastric ulcer caused by infection with Helicobacter pylori (H. pylori).

Over-the-counter (OTC) omeprazole is used in adults to help control heartburn that occurs 2 or more days per week. The OTC brand must be taken as a course on a regular basis for 14 days in a row.

Warnings

Omeprazole can cause kidney problems. Tell your doctor if you are urinating less than usual, or if you have blood in your urine.

Diarrhea may be a sign of a new infection. Call your doctor if you have diarrhea that is watery or has blood in it.

Omeprazole is not to used for the immediate relief of heartburn symptoms.

Omeprazole may cause new or worsening symptoms of lupus. Tell your doctor if you have joint pain and a ...