Onabotulinumtoxina (Intramuscular)
Medically reviewed by Drugs.com. Last updated on Mar 8, 2022.
Distant spread of toxin effects - The effects of onabotulinumtoxinA and all botulinum toxin products may spread from the area of injection to produce symptoms consistent with botulinum toxin effects. These symptoms have been reported hours to weeks after injection. Swallowing and breathing difficulties can be life threatening and there have been reports of death. The risk of symptoms is probably greatest in children treated for spasticity but symptoms can also occur in adults, particularly in those patients who have an underlying condition that would predispose them to these symptoms .
Commonly used brand name(s)
In the U.S.
- Botox
- Botox Cosmetic
Available Dosage Forms:
- Powder for Solution
Therapeutic Class: Musculoskeletal Agent
Pharmacologic Class: Botulinum Toxin Type A
Uses for onabotulinumtoxina
OnabotulinumtoxinA is used to treat certain eye conditions, such as blepharospasm (a condition where the eyelid will not stay open because of a muscle spasm) or strabismus (a condition where the eyes do not line up properly).
OnabotulinumtoxinA is also used to treat the abnormal head position and neck pain that result from cervical dystonia (severe muscle spasms of the neck) and some types of axillary hyperhidrosis (severe sweating of the armpits).
OnabotulinumtoxinA is used to treat increased muscle stiffness in the elbow, wrist, and finger muscles or ankle and toe muscles in adults with upper or lower limb spasticity or in children 2 to 17 years of age with upper and lower limb spasticity.
OnabotulinumtoxinA is also used to prevent headaches in patients with chronic migraine (severe headaches for 15 or more days a month lasting 4 or more hours a day).
OnabotulinumtoxinA is used cosmetically to temporarily improve the appearance of deep facial lines or wrinkles between the eyebrows (glabellar lines), forehead lines, and crow's feet lines around the eyes (lateral canthal lines).
OnabotulinumtoxinA is also used to treat urinary incontinence (loss of bladder control) in patients with an overactive bladder caused by nervous system disorders (eg, multiple sclerosis, spinal cord injury). It is also used to treat an overactive bladder caused by a nervous system disorder or overactive bladder with symptoms, such as loss of bladder control, increased urge to urinate, and frequent need to urinate in patients who have failed treatment with other medicines (eg, anticholinergics).
OnabotulinumtoxinA is a botulinum toxin A product. It works on the nervous system to relax the muscles.
OnabotulinumtoxinA is injected into the affected muscles. Depending on your condition, more than one treatment may be required.
Onabotulinumtoxina is available only with your doctor's prescription and will be administered by your doctor.
Before using onabotulinumtoxina
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For onabotulinumtoxina, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to onabotulinumtoxina or any other medicines. Also ..
