Oncaspar
Generic name:pegaspargase [ peg-ah-SPAR-jase ]
Drug class:Miscellaneous antineoplastics
What is Oncaspar?
Oncaspar is used in combination with other medicines to treat acute lymphoblastic leukemia.
Oncaspar is also used to treat allergic reactions to another cancer medicine called asparaginase.
Oncaspar may also be used for purposes not listed in this medication guide.
Warnings
You should not use Oncaspar if you are allergic to Oncaspar or asparaginase, if you have ever received asparaginase and it caused pancreatitis, severe bleeding, or a blood clot.
Before taking this medicine
You should not use this medicine if you are allergic to Oncaspar or asparaginase, or if you have ever received asparaginase and it caused any of the following conditions:
a blood clot;
pancreatitis;
severe bleeding; or
a severe allergic reaction.
Tell your doctor if you have ever had:
a pancreas disorder;
diabetes;
bleeding problems;
any allergies; or
a stroke or blood clot.
You may need to have a negative pregnancy test before starting this treatment.
Oncaspar may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 3 months after your last dose. Tell your doctor if you become pregnant.
Oncaspar can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. To prevent pregnancy while using this medicine, use a barrier form of birth control: condom, diaphragm, cervical cap, or contraceptive sponge.
Do not breastfeed while using this medicine, and for at least 3 months after your last dose.
How is Oncaspar given?
Oncaspar is injected into a muscle or given as an infusion into a vein. A healthcare provider will give you this injection.
You will be watched closely for at least 1 hour to make sure you do not have an allergic reaction.
Oncaspar can lower your blood cell counts. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results.
Your liver function may also need to be checked.
