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Onexton
  • Treatments
  • Acne

Onexton

Generic name:benzoyl peroxide and clindamycin topicalBEN-zoyl-per-OX-ide-and-clin-da-MYE-sin ]
Brand names: Acanya, BenzaClin, Duac, Neuac, Onexton, Z-Clinz 10, Z-Clinz 5
Drug class:Topical acne agents

Medically reviewed by Drugs.com on Sep 1, 2021. Written by Cerner Multum.

What is Onexton?

Benzoyl peroxide has an antibacterial effect. It also has a mild drying effect that allows excess oil and dirt to be washed away.

Clindamycin is an antibiotic that prevents bacteria from growing on the skin.

Onexton (for the skin) is a combination medicine used to treat acne.

Onexton may also be used for purposes not listed in this medication guide.

Warnings

Onexton can cause a rare but serious allergic reaction or severe skin irritation. Stop using this medicine and get emergency medical help if you have: hives, itching; difficult breathing, feeling light-headed; or swelling of your face, lips, tongue, or throat.

Before taking this medicine

You should not use this medicine if you are allergic to benzoyl peroxide or clindamycin (Cleocin, Clina-Derm, Clindets).

Although this medicine is applied to the skin, your body may absorb enough clindamycin to cause serious side effects. You may not be able to use this medicine if you have:

  • inflammation of your intestines (also called enteritis);

  • ulcerative colitis; or

  • if you have ever had severe diarrhea caused by antibiotic medicine.

It is not known whether Onexton will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

It is not known whether benzoyl peroxide and clindamycin topical passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

How should I use Onexton?

Follow all directions on your prescription label. Do not use Onexton in larger or smaller amounts or for longer than recommended.

Using more medicine or applying it more often than prescribed will not make it work any faster, and may increase side effects.

Benzoyl peroxide can cause a rare but serious allergic reaction or severe skin irritation. Before you start using this medicine, you may choose to apply a "test dose" to see if you have a reaction. Apply a very small amount of the medicine to 1 or 2 small acne areas every day for 3 days in a row. If t...