Generic name:opicapone [ oh-PIK-a-pone ]
Drug class:Dopaminergic antiparkinsonism agents
What is Ongentys?
Ongentys is a prescription medicine that inhibits the enzyme catechol-O-methyltransferase (COMT). COMT is involved in the degradation of certian neurotransmitters such as dopamine, epinephrine, and norepinephrine.
Ongentys is used together with carbidopa and levodopa to treat symptoms of "off" episodes (stiffness, tremors, muscle spasms, poor muscle control) in people with Parkinson's disease.
It is not known if Ongentys is safe and effective in children.
Warnings
Do not use Ongentys if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine and others.
Do not use Ongentys if you have a tumor that secretes hormones known as catecholamines. These tumors include pheochromocytoma (a type of adrenal gland tumor) and paraganglioma.
Before taking this medicine
You should not use Ongentys if you are allergic to opicapone, or if you have a certain type of tumor that secretes hormones, such as:
pheochromocytoma (tumor of the adrenal gland); or
paraganglioma (tumor of the nerve cells).
To make sure Ongentys is safe for you, tell your doctor if you have ever had:
a sleep disorder that causes daytime sleepiness;
