Onivyde
Generic name:irinotecan liposomal [ EYE-ri-noe-TEE-kan-LYE-poe-SOE-mal ]
Drug class:Miscellaneous antineoplastics
What is Onivyde?
Onivyde is used to treat pancreatic cancer that has spread to other parts of the body (metastatic). This medicine is usually given in combination with other cancer medicines.
Onivyde may also be used for purposes not listed in this medication guide.
Warnings
Onivyde can cause severe diarrhea, which can be life-threatening. Call your doctor whenever you have diarrhea during your treatment with Onivyde.
Before taking this medicine
You should not use this medicine if you are allergic to irinotecan.
Tell your doctor if you have ever had:
liver or kidney disease;
lung disease; or
an intestinal disorder or obstruction.
Onivyde can harm an unborn baby if the mother or the father is using this medicine.
If you are a woman, you may need to have a negative pregnancy test. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 1 month after your last dose.
If you are a man, use condoms if your sex partner is able to get pregnant. Keep using condoms for at least 4 months after your last dose.
Tell your doctor right away if a pregnancy occurs while either the mother or the father is using Onivyde.
Do not breastfeed while using this medicine, and for at least 1 month after your last dose.
How is Onivyde given?
Onivyde is given as an infusion into a vein. A healthcare provider will give you this injection.
Onivyde must be given slowly, and the infusion can take up to 90 minutes to complete.
Onivyde can cause severe diarrhea, which can be life-threatening if it leads to dehydration.
Your doctor may recommend keeping anti-diarrhea medicine on hand at all times (such as loperamide or Imodium). Take this medicine at the first sign of loose or frequent bowel movements. Do not take loperamide for longer than 2 full days without your doctor's advice.
Call your doctor whenever you have diarrhea during your treatment with Onivyde.
You may need frequent medical tests to be sure this medicine is not causing harmful effects. Your cancer treatments may be delayed based on the results.
