Generic name:patisiran [ PAT-i-SIR-an ]
Drug class:Miscellaneous metabolic agents
What is Onpattro?
Onpattro a double-stranded small interfering ribonucleic acid (siRNA), formulated as a lipid complex injection.
Onpattro is a prescription medicine used to treat polyneuropathy (damage of multiple nerves throughout the body) in adults with hereditary transthyretin-mediated amyloidosis (hATTR).
Onpattro is given by intravenous (IV) infusion.
Warnings
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
Before using Onpattro tell your doctor about all your medical conditions or allergies.
It is not known whether Onpattro will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of patisiran on the baby.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
How is Onpattro given?
Onpattro is given as an infusion into a vein. A healthcare provider will give you this injection once every 3 weeks.
This medicine must be given slowly, and the infusion can take about 80 minutes to complete.
Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Onpattro is injected.
You may be given other medications to help prevent serious side effects or an infusion reaction.
Your doctor may have you take extra vitamin A while you are using Onpattro. Take only the amount of vitamin A your doctor has prescri...
