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Opicapone
  • Treatments
  • Parkinson's Disease

Opicapone

Generic name: opicapone [ oh-PIK-a-pone ]
Brand name: Ongentys
Dosage form: oral capsule (25 mg; 50 mg)
Drug class:Dopaminergic antiparkinsonism agents

Medically reviewed by Drugs.com on Aug 3, 2021. Written by Cerner Multum.

What is opicapone?

Opicapone is used together with carbidopa and levodopa to treat symptoms of "off" episodes (stiffness, tremors, muscle spasms, poor muscle control) in people with Parkinson's disease.

Opicapone may also be used for purposes not listed in this medication guide.

Warnings

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Before taking this medicine

You should not use opicapone if you are allergic to it, or if you have a certain type of tumor that secretes hormones, such as:

Do not use opicapone if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.

Tell your doctor if you have ever had:

  • a sleep disorder that causes daytime sleepiness;

  • narcolepsy or other conditions that cause sudden sleepiness;

  • uncontrolled muscle movements;

  • unusual and intense urges to act on impulse (such as gambling, binge-eating, or compulsive shopping);

  • mental illness, hallucinations, or psychosis;

  • liver disease; or

  • kidney disease.

Tell your doctor if you are pregnant or breastfeeding.

How should I take opicapone?

When you start or stop taking opicapone, your doctor may need to adjust the doses of any other medicines you take for Parkinson's disease.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Opicapone is usually taken at bedtime, on an empty stomach.

Do ...