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Oritavancin
  • Treatments
  • Skin and Structure Infection

Oritavancin

Generic name: oritavancin [ or-IT-a-VAN-sin ]
Brand names: Kimyrsa, Orbactiv
Dosage form: intravenous powder for injection (1200 mg; 400 mg)
Drug class:Glycopeptide antibiotics

Medically reviewed by Drugs.com on Jun 15, 2021. Written by Cerner Multum.

What is oritavancin?

Oritavancin is an antibiotic that is used to treat severe skin infections caused by bacteria.

Oritavancin may also be used for purposes not listed in this medication guide.

Warnings

Tell your doctor if you use other medicines or have other medical conditions or allergies.

Before taking this medicine

You should not receive oritavancin if you are allergic to it, or if you will be using "unfractionated" heparin within 5 days after your receive oritavancin injection.

Tell your doctor if you have ever had:

  • an allergic reaction to medicines such as dalbavancin, telavancin, or vancomycin; or

  • if you use a blood thinner (such as warfarin) and you have routine "INR" or prothrombin time tests.

Tell your doctor if you are pregnant or breastfeeding.

Oritavancin is not approved for use by anyone younger than 18 years old.

How is oritavancin given?

Oritavancin is injected into a vein by a healthcare provider, usually as a single dose.

oritavancin is injected slowly over 3 hours.

Call your doctor promptly if your symptoms do not improve after receiving oritavancin.

Oritavancin can affect the results of certain medical tests for up to 5 days after your injection. Tell any doctor who treats you that you have been treated with oritavancin.

What happens if I miss a dose?

Since oritavancin is given in a single dose, it does not have a daily dosing schedule.

What happens if I overdose?

In a medical setting an overdose would be treated quickly.

What should I avoid after receiving oritavancin?

Avoid taking anti-diarrhea medicine without first asking your doctor. Diarrhea may be a sign of a new infection.

For at least 5 days after receiving oritavancin, avoid using heparin.

Oritavancin side effects

Get emergency medical help if you have signs of an allergic reaction:hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects may occur during the injection. Tell your caregiver right away if you feel warm, itchy, dizzy, light-headed, sweaty, or have chills, tremors, chest