Orphengesic (Oral)

Generic name:orphenadrine, aspirin, and caffeine (oral route) [ or-FEN-a-dreen-SIT-rate, AS-pir-in, KAF-een ]
Drug class:Skeletal muscle relaxant combinations

Medically reviewed by Drugs.com. Last updated on May 17, 2022.

Commonly used brand name(s)

In the U.S.

• Norgesic
• Norgesic Forte
• Orphenadrine w/A.C.
• Orphengesic
• Orphengesic Forte

Available Dosage Forms:

• Tablet

Therapeutic Class: Skeletal Muscle Relaxant, Centrally Acting/Salicylate, Aspirin Combination

Pharmacologic Class: Orphenadrine

Chemical Class: Salicylate, Aspirin

Uses for Orphengesic

Orphenadrine, aspirin, and caffeine combination is used to relieve mild to moderate pain in patients with acute (short-term) muscle or bone problems. It helps relax certain muscles in your body, which relieves the pain and discomfort caused by strains, sprains, or other injury to your muscles. However, this medicine does not take the place of rest, exercise, or other treatment that your doctor may recommend for your medical problem.

Orphenadrine acts in the central nervous system (CNS) to produce its muscle relaxant effects. Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain and reduce fever. Caffeine is a CNS stimulant that is used together with pain relievers to increase their effect.

This medicine is available only with your doctor's prescription.

Before using Orphengesic

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Because of aspirin's toxicity, use in children younger than 12 years of age is not recommended. Do not give aspirin to a child who has chickenpox or flu symptoms, unless approved by a doctor.

Geriatric

No information is available on the relationship of age to the effects of orphenadrine, aspirin, and caffeine combination in geriatric patients.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other pre...