Osimertinib
Generic name: osimertinib [ OH-sim-ER-ti-nib ]
Brand name: Tagrisso
Dosage form: oral tablet (40 mg; 80 mg)
Drug class:EGFR inhibitors
What is osimertinib?
Osimertinib is used to treat non-small cell lung cancer that is positive for an abnormal "EGFR" gene. You doctor will test you for this gene.
Osimertinib is sometimes given when the cancer has spread to other parts of the body (metastatic), or may come back after surgery.
Osimertinib may also be used for purposes not listed in this medication guide.
Warnings
Osimertinib can cause serious side effects on your heart, lungs, skin, or eyes.
Call your doctor at once if you have fast or pounding heartbeats, swelling in your lower legs, fever, cough, trouble breathing, skin blistering or peeling, vision changes, eye pain, increased sensitivity to light, or if you feel light-headed or short of breath.
Before taking this medicine
You should not use osimertinib if you are allergic to it.
Tell your doctor if you have ever had:
lung or breathing problems;
an electrolyte imbalance (such as high or low blood levels of sodium, calcium, potassium, or magnesium);
eye problems; or
heart problems, including long QT syndrome (in you or a family member).
Osimertinib can harm an unborn baby if the mother or the father is using osimertinib.
If you are a woman, you may need a pregnancy test to make sure you are not pregnant. Use birth control while using this medicine and for at least 6 weeks after your last dose.
If you are a man, use birth control if your sex partner is able to get pregnant. Keep using birth control for at least 4 months after your last dose.
Tell your doctor right away if a pregnancy occurs.
Pregnancy may be less likely to occur while the mother or the father is using this medicine. Both men and women should still use birth control to prevent pregnancy because the medicine can harm an unborn baby.
Do not breastfeed while using this medicine, and for at least 2 weeks after your last dose.
How should I take osimertinib?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Osimertinib is usually given once per day, with or without food.
To make swallowing easier, you may place the tablet in a glass with about 2 ounces of water. Stir until the tablet is mostly dissolved and drink this mixture right away. Add 4 to 8 ounces more wa...
