OtiRx Ear Drops

Generic name:hydrocortisone, pramoxine hydrochloride, and chloroxylenol
Dosage form: ear drops
Drug class:Otic steroids with anti-infectives

Medically reviewed by Drugs.com. Last updated on Dec 22, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

OtiRx Ear Drops Description

OtiRx™ Ear Drops is an anti-inflammatory, antimicrobial and local anesthetic solution for use in the external ear only.

Each 1 mL contains:

Inactive Ingredients: Propylene Glycol and Isopropyl Alcohol.

Hydrocortisone (Cortisol)(Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-,(11β)–.) is an anti-inflammatory and antipruritic agent. Pramoxine (Morpholine, 4-[3-(4-butoxyphenoxy) propyl]-,hydrochloride), is a topical anesthetic. Chloroxylenol (4-Chloro-3,5-xylenol) is a wide spectrum antimicrobial agent.

OtiRx Ear Drops - Clinical Pharmacology

Hydrocortisone is a corticosteroid which has anti-inflammatory, antipruritic and vasoconstrictive actions. The mechanism of anti-inflammatory action of topical corticosteroids is unclear. Topical corticosteroids can be absorbed from normal intact skin. Inflammation and/or other disease processes in the skin increase percutaneous absorption. Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically-administered corticosteroids. Corticosteroids are bound to plasma proteins in varying degrees. Corticosteroids are metabolized primarily in the liver and are then excreted...