Oto End 10

Generic name:pramoxine hcl, hydrocortisone, chloroxylenol
Dosage form: otic solution
Drug class:Otic steroids with anti-infectives

Medically reviewed by Drugs.com. Last updated on Jun 21, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

Oto End 10 Description

Oto-End 10 Ear Drops is an anti-inflammatory, antimicrobial and local anesthetic solution for use in the external ear only.

Each 1 mL for otic administration contains:

Hydrocortisone . . . . . . . . . . . . . . 10 mg

Pramoxine Hydrochloride . . . . . . 10 mg

Chloroxylenol . . . . . . . . . . . . . . . . 1 mg

Hydrocortisone (cortisol) is an anti-inflammatory and antipruritic agent. It is a white to practically white, odorless, crystalline powder, very slightly soluble in water. It has the chemical name Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-,(11β)- and the following structural:

C 21H 30O 5
M.W. 362.46

Pramoxine hydrochloride is a topical anesthetic. Used as the hydrochloride salt, it has the chemical name Morpholine, 4-[3-(4-butoxyphenoxy)propyl]-, hydrochloride.

C 17H 27NO 3 • HCl
M.W. 329.86

Chloroxylenol (4-chloro-3, 5-dimethyl phenol or meta-chloro-xylenol) is a wide spectrum antimicrobial agent. It has the following structural formula.

C 8H 9ClO
M.W. 156.61

INACTIVE INGREDIENTS

In a non aqueous vehicle containing edetate disodium EDTA, Poloxamer 188, propylene glycol, propylene glycol diacetate, propylgallate,