Oxymetazoline Cream

Generic name: oxymetazoline hydrochloride
Dosage form: cream
Drug class:Topical anti-rosacea agents

Medically reviewed by Drugs.com. Last updated on Oct 1, 2021.

Indications and Usage for Oxymetazoline Cream

Oxymetazoline hydrochloride cream is indicated for the topical treatment of persistent facial erythema associated with rosacea in adults.

Oxymetazoline Cream Dosage and Administration

For topical use only. Oxymetazoline hydrochloride is not for oral, ophthalmic, or intravaginal use.

Apply a pea-sized amount of oxymetazoline hydrochloride cream, once daily in a thin layer to cover the entire face (forehead, nose, each cheek, and chin) avoiding the eyes and lips. Wash hands immediately after applying oxymetazoline hydrochloride cream.

Dosage Forms and Strengths

Oxymetazoline hydrochloride cream, 1% is a white to off-white cream. Each gram of cream contains 10 mg (1%) oxymetazoline hydrochloride, equivalent to 8.8 mg (0.88%) of oxymetazoline free base.

Contraindications

None.

Warnings and Precautions

Potential Impacts on Cardiovascular Disease

Alpha-adrenergic agonists may impact blood pressure. Oxymetazoline hydrochloride should be used with caution in patients with severe or unstable or uncontrolled cardiovascular disease, orthostatic hypotension, and uncontrolled hypertension or hypotension. Advise patients with cardiovascular disease, orthostatic hypotension, and/or uncontrolled hypertension/hypotension to seek immediate medical care if their condition worsens.

Potentiation of Vascular Insufficiency

Oxymetazoline hydrochloride should be used with caution in patients with cerebral or coronary insufficiency, Raynaud's phenomenon, thromboangiitis obliterans, scleroderma, or Sjögren's syndrome. Advise patients to seek immediate medical care if signs and symptoms of potentiation of vascular insufficiency develop.