Antivenin North American Coral Snake

Generic name: coral snake (micrurus fulvius) immune globulin antivenin (equine)
Dosage form: injection, powder, for solution

Indications and Usage for Antivenin North American Coral Snake

North American Coral Snake Antivenin (Equine) is indicated only for the treatment of envenomation caused by bites of North American coral snakes - Micrurus (including the eastern and Texas varieties).

Antivenin North American Coral Snake Dosage and Administration

For intravenous use only.

Dose

• Contents of each reconstituted vial can neutralize approximately 250 mouse (Lethal Dose) LD50 or approximately 2 mg of Micrurus fulvius fulvius (M. f. fulvius) venom.
• In adults and adolescents, the dose may vary from 3 to 5 vials, depending on the response to treatment.
• In small children, the dose may be decreased, depending on the response to treatment.

Preparation and Administration

Preparation

• Pry off the small metal disc in the cap over the diaphragms of the vials of North American Coral Snake Antivenin (Equine) and remove cap from diluent vials.
• Swab the exposed surface of the rubber diaphragms of both vials with an appropriate germicide.
• Withdraw 10 mL diluent (Sterile Water for Injection, USP) using a sterile syringe and needle, and insert the needle through the stopper of the vacuum-containing vial of North American Coral Snake Antivenin (Equine).
  • The vacuum in the North American Coral Snake Antivenin (Equine) vial will pull the diluent out of the syringe into the vial. Allow room air to be pulled into the North American Coral Snake Antivenin (Equine) vial until all vacuum is released.
  • Point the needle at the center of the lyophilized pellet of North American Coral Snake Antivenin (Equine) so that the diluent stream will wet the pellet.
• Reconstitute by swirling, not by shaking, for 1 minute, at 5-minute intervals until you observe complete dissolution of the lyophilized North American Coral Snake Antivenin (Equine). Complete reconstitution usually requires at least 30 minutes.

Administration

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