Peginesatide (Injection)

Medically reviewed by Drugs.com. Last updated on Dec 30, 2021.

Injection route(Solution)

Erythropoiesis-stimulating agents (ESAs) increase the risks for death, myocardial infarction, stroke, and other serious cardiovascular events. In clinical studies, patients with chronic kidney disease (CKD) had a greater risk for death, serious adverse cardiovascular reactions, and stroke when administered ESAs to target Hb levels of 11 g/dL or higher. No trial has identified a Hb target level, ESA dose, or dosing strategy that does not increase these risks. Therefore, in patients with CKD, use the lowest sufficient dose to reduce the need for RBC transfusion .

Pharmacologic Class: Erythropoietic

Uses for peginesatide

Peginesatide injection is used to treat anemia in patients with chronic kidney disease (CKD) who are on dialysis.

Peginesatide was available only with your doctor's prescription.

Peginesatide was voluntarily withdrawn from the U.S. market on February 24, 2013 due to safety concerns for serious allergic reactions.

Before using peginesatide

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For peginesatide, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to peginesatide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of peginesatide injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of peginesatide injection in the elderly.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Peginesatide Injection