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Perampanel
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Perampanel

Generic name: perampanel [ per-AM-pa-nel ]
Brand name: Fycompa
Dosage forms: oral suspension (0.5 mg/mL); oral tablet (10 mg; 12 mg; 2 mg; 4 mg; 6 mg; 8 mg)
Drug class:AMPA receptor antagonists

Medically reviewed by Drugs.com on Aug 5, 2021. Written by Cerner Multum.

What is perampanel?

Perampanel is an anticonvulsant that is used to treat partial onset seizures that may or may not develop into general seizures in people with epilepsy who are at least 4 years old.

Perampanel is also used to treat tonic-clonic seizures in people with epilepsy who are at least 12 years old.

Perampanel may also be used for purposes not listed in this medication guide.

Warnings

Some people taking perampanel have had serious psychotic effects, especially when starting perampanel or changing doses. Stay alert to changes in your mood or symptoms.

Call your doctor right away if you have any changes in mood or behavior changes, personality changes, thoughts about suicide, or thoughts about hurting others. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Before taking this medicine

You should not use perampanel if you are allergic to it.

Tell your doctor if you have ever had:

Some people taking perampanel have had serious psychotic effects such as anger, aggression, feeling hostile or irritable, and thoughts about hurting others. These effects may be more likely to occur when you first start taking perampanel, or whenever your dose is changed. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Do not start or stop taking seizure medication during pregnancy without your doctor's advice. Having a seizure during pregnancy could harm both mother and baby. Tell your doctor right away if you become pregnant.

Perampanel can make some birth control pills less effective. Ask your doctor about using a non-hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of perampanel on the baby.

It may not be safe to ...