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Percogesic Extra Strength
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Percogesic Extra Strength

Generic name:acetaminophen and diphenhydramine [ a-SEET-a-MIN-oh-fen-and-DYE-fen-HYE-dra-meen ]
Drug class:Analgesic combinations

Medically reviewed by Philip Thornton, DipPharm. Last updated on Jan 12, 2022.

What is Percogesic Extra Strength?

Percogesic Extra Strength contains a combination of acetaminophen and diphenhydramine. Acetaminophen is a pain reliever and a fever reducer. Diphenhydramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Percogesic Extra Strength is used to treat headache, backache, muscular aches, arthritis pain, colds, flu, fever, toothache, premenstrual and menstrual cramps.

Percogesic Extra Strength is also used for the temporary relief of runny nose, sneezing, itchy nose and throat.

Warnings

Do not take more Percogesic Extra Strength than is recommended. An overdose of acetaminophen can damage your liver or cause death.

In rare cases, acetaminophen may cause a severe skin reaction. Stop taking Percogesic Extra Strength and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.

Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.

Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen.

Before taking this medicine

Ask a doctor before taking medicine that contains acetaminophen if you have ever had liver disease, or if you drink more than 3 alcoholic beverages per day.

You should not use Percogesic Extra Strength if you are allergic to acetaminophen and diphenhydramine, or if you have:

  • severe constipation, blockage in your stomach or intestines;

  • untreated or uncontrolled diseases - glaucoma, asthma, heart disease, overactive thyroid; or

  • if you are unable to urinate.

Ask a doctor or pharmacist before taking Percogesic Extra Strength if you have any medical condition, especially:

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