Perphenazine

Generic name: perphenazine [ per-FEN-a-zeen ]
Brand name: Trilafon
Dosage form: oral tablet (16 mg; 2 mg; 4 mg; 8 mg)
Drug classes:Phenothiazine antiemetics, Phenothiazine antipsychotics

Medically reviewed by Drugs.com on Apr 14, 2022. Written by Cerner Multum.

What is perphenazine?

Perphenazine is a phenothiazine (FEEN-oh-THYE-a-zeen) anti-psychotic medicine.

Perphenazine is used to treat psychotic disorders such as schizophrenia. It is also used to control severe nausea and vomiting.

Perphenazine may also be used for purposes not listed in this medication guide.

Warnings

You should not use perphenazine if you have liver disease, brain damage, bone marrow depression, a blood cell disorder, or if you are also using large amounts of alcohol or medicines that make you sleepy.

Perphenazine is not approved for use in older adults with dementia-related psychosis.

Call your doctor at once if you have twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs. These could be early signs of dangerous side effects.

Before taking this medicine

You should not use perphenazine if you are allergic to any phenothiazine (such as perphenazine, chlorpromazine, prochlorperazine, promethazine, o thioridazine), or if you...