Pertuzumab
Generic name: pertuzumab [ per-TOO-zoo-mab ]
Brand name: Perjeta
Dosage form: intravenous solution (420 mg/14 mL)
Drug class:HER2 inhibitors
What is pertuzumab?
Pertuzumab is used together with other medicines (trastuzumab and docetaxel) to treat HER2-positive breast cancer.
Pertuzumab may also be used for purposes not listed in this medication guide.
Warnings
Pertuzumab can cause birth defects or death to the unborn baby. Do not use if you are pregnant. Avoid getting pregnant while using pertuzumab and for at least 7 months after your last dose.
Pertuzumab can cause life-threatening heart problems. Call your doctor at once if you have new or worsening cough, shortness of breath, or swelling in your lower legs.
Before taking this medicine
You should not use pertuzumab if you are allergic to it, or if you are pregnant or breast-feeding.
Tell your doctor if you have ever had:
heart disease, congestive heart failure, heart rhythm disorder;
untreated or uncontrolled high blood pressure (hypertension);
a heart attack; or
radiation treatment in your chest area.
Do not use pertuzumab if you are pregnant. It can cause birth defects or death to the unborn baby. Use effective birth control to prevent pregnancy while you are using pertuzumab with trastuzumab, and for at least 7 months after your treatment ends. Tell your doctor right away if you become pregnant.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of pertuzumab on the baby.
It may not be safe to breastfeed while using pertuzumab with trastuzumab, and for up to 7 months after your last dose. Ask your doctor about any risk.
How is pertuzumab given?
Pertuzumab is given as an infusion into a vein. A healthcare provider will give you this injection.
Pertuzumab is usually given once every 3 weeks. Follow your doctor's instructions.
Pertuzumab can cause life-threatening heart problems. Your heart function may need to be checked before you start using pertuzumab and during your treatment.